Share this postDeets On The Evolution of CRISPR, Cas9, and mRNA Technologywww.deets.blogCopy linkFacebookEmailNoteOtherDeets On The Evolution of CRISPR, Cas9, and mRNA TechnologyDeets On Public HealthRon DeetsSep 21, 2023Share this postDeets On The Evolution of CRISPR, Cas9, and mRNA Technologywww.deets.blogCopy linkFacebookEmailNoteOtherShareDeets On The Evolution of CRISPR, Cas9, and mRNA Technology (In Progress)“CRISPR Cas9 (41124064215)” under public domain from CRISPR Cas9 by NIH Image Gallery.Polymers for the sustained release of proteins and other macromolecules – Nature October 28, 1976Genetic Material of Virus From 1918 Flu Is Found – The New York Times March 21, 1997RNA virus mutations and fitness for survival – NIH PubMed 1997Celera Is At It Again - WIRED July 17, 2000FDA Halts Gene Therapy Studies – NPR January 15, 2003Genome Hunters – NPR March 5, 2004Gene Therapy Promising for Treating ‘Bubble’ Children – NPR December 27, 2004A Scalable, Extrusion-Free Method for Efficient Liposomal Encapsulation of Plasmid DNA – SpringerLink March 21, 2005Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA – ScienceDirect August 2005Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA- NIH PubMed August 23, 2005The Nobel Prize in Physiology or Medicine 2006 – Nobel Prizes & Laureates October 13, 2006CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes – Science March 23, 2007Are We One Step Closer to Artificial Life? – June 29, 2007Researchers Pin Down Genome of Parasitic Worms – NPR September 25, 2007Venter ‘Decodes’ Genome Project Controversy – NPR November 5, 2007Genetic First: Bacterium’s Code Built from Scratch – NPR January 24, 2008Advances in Gene Therapy Treatment for Blindness – NPR May 2, 2008Scientists Engineer Viruses To Battle Bacteria – NPR March 6, 2009DNA Transplant Transforms Bacteria – NPR August 21, 2009A Potential But Controversial Fix For Genetic Disease – NPR August 26, 2009Thanks To Gene Therapy, Monkeys See In Full Color – NPR September 17, 2009Examining Gene Therapy As Treatment For Blindness – NPR October 30, 2009Rare Disease Treated Using Gene Therapy – NPR November 5, 2009Emergence of a group 3 coronavirus through recombination – ScienceDirect March 1, 2010Scientists Still Hopeful About Gene Therapy’s Promise – NPR March 8, 2010A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity – Science June 28, 2012A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity – NIH PubMed August 17, 2012Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria – PNAS September 4, 2012Looking To Nature For Antibiotic Inspirations – NPR April 12, 2013Proposed Treatment To Fix Genetic Diseases Raises Ethical Issues – NPR October 9, 2013Biosecurity for the Age of Redesigned Life – NPR November 8, 2013Gene Therapy Keeps ‘Bubble Boy’ Disease At Bay In 8 Children – NPR December 7, 2013CRISPR-Cas systems for editing, regulating and targeting genomes – Nature March 2, 2014A semi-synthetic organism with an expanded genetic alphabet – Nature May 7, 2014A CRISPR Way To Fix Faulty Genes – NPR June 26, 2014A cluster randomised trial of cloth masks compared with medical masks in healthcare workers – BMJ September 9, 2014In Hopes Of Fixing Faulty Genes, One Scientist Starts With The Basics – NPR October 13, 2014Why Bio is the New Digital | Joi Ito keynotev – O’Reilly June 25, 2015Who discovered messenger RNA? – Cell Press June 29, 2015And Science’s 2015 Breakthrough of the Year is… – Science December 17, 2015Vaccine Testing and the Approval Process – CDC.GOV February 9, 2016Pre-fusion structure of a human coronavirus spike protein- NIH PubMed March 3, 2016U.S. public opinion on the future use of gene editing – Pew Research Center July 26, 2016What is CRISPR-Cas? – Microbiology Society August 9, 2016Genetic Engineering Will Change Everything Forever – CRISPR – Kurzgesagt – In a Nutshell August 10, 2016Science Rewards Eureka Moments, Except When It Doesn’t – NPR November 2, 2016Scientists Battle In Court Over Lucrative Patents For Gene-Editing Tool – NPR December 5, 2016PD-1 Knockout Engineered T Cells for Advanced Esophageal Cancer – ClinicalTrials.gov March 16, 2017 How A Gene Editing Tool Went From Labs To A Middle-School Classroom – NPR May 27, 2017Americans divided on gene editing, with parents of minors more wary – Pew Research Center August 8, 2017People Back Editing Genes To Treat Disease, But Are Wary Of Inheritable Changes – NPR August 10, 2017Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen – PNAS August 14, 2017Prefusion coronavirus spike proteins and their use- Justia Patents October 25, 2017mRNA vaccines — a new era in vaccinology – nature reviews January 12, 2018NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells) – ClinicalTrials.GOV January 16, 2018Doctors In China Lead Race To Treat Cancer By Editing Genes – NPR February 21, 2018The Global Virome Project – Science February 23, 2018Inside the secret U.S. stockpile meant to save us all in a bioterror attack – The Washington Post April 24, 2018The Next Phase of Human Gene-Therapy Oversight – The New England Journal of Medicine October 11, 2018Broad-Spectrum Antiviral Agents: A Crucial Pandemic Tool – Taylor & Francis Online March 12, 2019Single Ascending Dose Study in Participants With LCA10 – ClinicalTrials.GOV March 13, 2019First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway – NPR April 16, 2019Scientists Modify Viruses With CRISPR To Create New Weapon Against Superbugs – NPR May 22, 2019In A 1st, Doctors In U.S. Use CRISPR Tool To Treat Patient With Genetic Disorder – NPR July 29, 2019A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON) – ClinicalTrials.GOV July 29, 2019Search-and-replace genome editing without double-strand breaks or donor DNA – Nature August 21, 2019CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows – NPR September 11, 2019Delivery system can make RNA vaccines more powerful – MIT News September 30, 2019A Patient Hopes Gene-Editing Can Help With Pain Of Sickle Cell Disease – NPR October 10, 2019Scientists Create New, More Powerful Technique To Edit Genes – NPR October 21, 2019NIH launches new collaboration to develop gene-based cures for sickle cell disease and HIV on global scale – NIH October 23, 2019Is Crispr the Next Antibiotic? – The New York Times October 28, 2019A Revolutionary Experiment To Edit Human Genes – NPR November 4, 2019CRISPR Approach To Fighting Cancer Called ‘Promising’ In 1st Safety Test – NPR November 6, 2019Molecular Scissors Could Help Keep Some Viral Illnesses At Bay – NPR November 13, 2019A New Way To Stop Viruses – NPR November 13, 2019Gene-Edited ‘Supercells’ Make Progress In Fight Against Sickle Cell Disease – NPR November 19, 2019Gene Therapy May Aid In Sickle Cell Disease Treatment – NPR December 10, 2019A Young Mississippi Woman’s Journey Through A Pioneering Gene-Editing Experiment – NPR December 25, 2019How Computer Modeling Of COVID-19’s Spread Could Help Fight The Virus – NPR March 4, 2020Where’s The Vaccine? – NPR March 6, 2020Iranian, Russian, Chinese Media Push COVID-19 ‘Bioweapon’ Conspiracies – Defense One March 10, 2020WHO declares coronavirus a pandemic, urges aggressive action – AP News March 11, 2020The 4 Key Reasons the U.S. Is So Behind on Coronavirus Testing – The Atlantic March 13, 2020Coronavirus Symptoms: Defining Mild, Moderate And Severe – NPR March 13, 2020Trump disbanded NSC pandemic unit that experts had praised – AP News March 14, 2020Hackers Attack Health and Human Services Computer System – The New York Times March 16, 2020NIH clinical trial of investigational vaccine for COVID-19 begins – NIH March 16, 2020Russia deploying coronavirus disinformation to sow panic in West, EU document says - EURACTIV March 18, 2020The Coronavirus Explained & What You Should Do – Kurzgesagt – In a Nutshell March 19, 2020Fact-Checking 5 Trump Administration Claims On The Coronavirus Pandemic – NPR March 21, 2020Why Is The Coronavirus So Good At Spreading? – NPR March 24, 2020Senate Passes $2 Trillion Coronavirus Relief Package – NPR March 25, 2020READ: $2 Trillion Coronavirus Relief Bill – NPR March 25, 2020Coronavirus in Russia: How Putin’s disinformation efforts could backfire at home - Bulletin of the Atomic Scientists March 31, 2020Trump administration ended pandemic early-warning program to detect coronaviruses – Los Angeles Times April 2, 2020OAN – Last Week Tonight with John Oliver April 6, 2020Could Society Move Toward Normalcy Before A Coronavirus Vaccine Is Ready? – NPR April 6, 2020Putin’s Long War Against American Science - The New York Times April 13, 2020Top Wall Street Regulators Warn Against Coronavirus Investment Scams – NPR April 15, 2020How Digital Contact Tracing Slowed Covid-19 in East Asia – Harvard Business Review April 15, 2020Coronaviruses – a brief history – The Conversation April 15, 2020CRISPR And Spit Might Be Keys To Faster, Cheaper, Easier Tests For The Coronavirus – NPR April 17, 2020Cytokine release syndrome in severe COVID-19 - Science April 17, 2020Taiwan hasn’t needed lockdowns to fight the coronavirus, but it simulated one anyway – QUARTZ April 20, 2020NIH Panel Recommends Against Drug Combination Promoted By Trump For COVID-19 – NPR April 21, 2020Director of U.S. agency key to vaccine development leaves role suddenly amid coronavirus pandemic – STAT April 21, 2020How Scientists Could Stop the Next Pandemic Before It Starts – The New York Times April 21, 2020Chinese Agents Helped Spread Messages That Sowed Virus Panic in U.S., Officials Say – The New York Times April 22, 2020Vaccine Chief Says He Was Removed After Questioning Drug Trump Promoted – The New York Times April 22, 2020Federal Scientist Says He Was Removed For Resisting Unproven Coronavirus Treatments – NPR April 22, 2020Social Distancing Is Working, According To Your Cellphone Data - wbur NPR April 23, 2020Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2 – NIH PubMed April 24, 2020Trump Muses About Light as Remedy, but Also Disinfectant, Which Is Dangerous – The New York Times April 24, 2020Trump’s Suggestion That Disinfectants Could Be Used to Treat Coronavirus Prompts Aggressive Pushback – The New York Times April 24, 2020The Controversial Experiments and Wuhan Lab Suspected of Starting the Coronavirus Pandemic – Newsweek April 27, 2020How Trump Gutted Obama’s Pandemic-Preparedness Systems – Vanity Fair May 1, 2020Obama team left pandemic playbook for Trump administration, officials confirm – PBS May 15, 2020U.S. and Chinese Scientists Trace Evolution of Coronaviruses in Bats – The New York Times June 1, 2020Abortion opponents protest COVID-19 vaccines' use of fetal cells - Science June 5, 2020Coronavirus Can Set Off a ‘Cytokine Storm.’ These Drugs May Calm It. - The New York Times June 11, 2020Twitter takes down China-linked accounts spreading disinformation on Hong Kong and coronavirus – CNBC June 12, 2020The COVID-19 Cytokine Storm; What We Know So Far - NIH PubMed June 16, 2020How to Stop Cancer Using RNA – SciShow June 24, 2020How fake accounts constantly manipulate what you see on social media – and what you can do about it – The Conversation June 24, 2020Russian disinformation in the time of Covid-19 - The Conversation July 8, 2020Pulmonary pathology and COVID-19: lessons from autopsy. The experience of European Pulmonary Pathologists – NIH PubMed July 9, 2020Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 – The New England Journal of Medicine July 9, 2020Anti-vaccination leaders fuel black mistrust of medical establishment as covid-19 kills people of color – The Washington Post July 17, 2020Coronavirus: Conspiracy Theories – Last Week Tonight with John Oliver July 20, 2020Covid-19 conspiracy theories are being fed by institutions meant to inform the public - Vox July 26, 2020US officials: Russia behind spread of virus disinformation - AP News July 28, 2020The great broadband divide – CBS Sunday Morning August 2, 2020A Top Vaccine Expert Answers Important Questions About a COVID-19 Vaccine – Johns Hopkins University August 5, 2020Fauci warns COVID-19 vaccine may be only partially effective, public health measures still needed - Reuters August 7, 2020Russian-backed organizations amplifying QAnon conspiracy theories, researchers say – Reuters August 24, 2020Experts: mRNA vaccine for COVID-19 does not alter DNA – AP News September 4, 2020How the pandemic distorted time – Vox September 7, 2020The Coronavirus: What Scientists Have Learned So Far – The New York Times September 9, 2020Historian predicts Trump downplaying pandemic will go down as ‘the greatest dereliction of duty’ in presidential history – The Hill September 10, 2020Trump held six indoor rallies after acknowledging the coronavirus was airborne - CBS News September 10, 2020Trump's first indoor rally since June defies Covid laws, attacks Biden - The Guardian September 14, 2020Study Finds ‘Single Largest Driver’ of Coronavirus Misinformation: Trump - The New York Times September 30, 2020Thank you for reading Deets On Politics. 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